Chemical customization involves tailoring drug formulations at a molecular level to match the unique characteristics of individual patients. This approach departs from traditional one-size-fits-all treatments and recognizes that patients have distinct genetic, molecular, and environmental attributes influencing treatment response. By customizing drug structures based on these factors, pharmaceutical scientists can optimize efficacy while minimizing adverse effects through precise, targeted delivery. The emergence of such bespoke therapy marks a paradigm shift towards truly personalized interventions, enabling better outcomes by aligning medication to patients’ genetic makeup and disease profile.